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T(H)1-Dominant Granulomatous Pathology Does Not Inhibit Fibrosis or Cause Lethality during Murine Schistosomiasis
Schistosoma mansoni egg-induced inflammation is accompanied by T(H)2 cell polarization and development of fibrotic granulomas in host tissue. The interleukin (IL)-4 receptor α (IL-4Rα), which mediates IL-4 and IL-13 signaling, is essential for granulomatous pathology through a putative CD4(+) T-cell...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1780204/ https://ncbi.nlm.nih.gov/pubmed/17071593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060346 |
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