Endogenous IL-13 Plays a Crucial Role in Liver Granuloma Maturation During Leishmania donovani Infection, Independent of IL-4Rα–Responsive Macrophages and Neutrophils

Previous studies comparing interleukin 4 receptor α (IL-4Rα)(-/-) and interleukin 4 (IL-4)(-/-) BALB/c mice have indicated that interleukin 13 (IL-13), whose receptor shares the IL-4Rα subunit with IL-4, plays a protective role during visceral leishmaniasis. We demonstrate that IL-13(-/-) BALB/c mic...

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Detalhes bibliográficos
Main Authors: McFarlane, Emma, Carter, Katharine C., McKenzie, Andrew N., Kaye, Paul M., Brombacher, Frank, Alexander, James
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105032/
https://ncbi.nlm.nih.gov/pubmed/21628656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir080
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