Functional Characterization of Alternate Optimal Solutions of Escherichia coli's Transcriptional and Translational Machinery

The constraint-based reconstruction and analysis approach has recently been extended to describe Escherichia coli's transcriptional and translational machinery. Here, we introduce the concept of reaction coupling to represent the dependency between protein synthesis and utilization. These coupl...

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Detalhes bibliográficos
Main Authors: Thiele, Ines, Fleming, Ronan M.T., Bordbar, Aarash, Schellenberger, Jan, Palsson, Bernhard Ø.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Biological Systems and Multicellular Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872367/
https://ncbi.nlm.nih.gov/pubmed/20483314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.060
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