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Reliable and efficient solution of genome-scale models of Metabolism and macromolecular Expression
Constraint-Based Reconstruction and Analysis (COBRA) is currently the only methodology that permits integrated modeling of Metabolism and macromolecular Expression (ME) at genome-scale. Linear optimization computes steady-state flux solutions to ME models, but flux values are spread over many orders...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241643/ https://ncbi.nlm.nih.gov/pubmed/28098205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40863 |
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