Characterization of oligonucleotide transport into living cells.

Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These compounds are taken up by cells in a saturable, size-dependent manner compatible with receptor-mediate...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, Cohen, J S, Neckers, L M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3474
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