Characterization of oligonucleotide transport into living cells.
Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These compounds are taken up by cells in a saturable, size-dependent manner compatible with receptor-mediate...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1989
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3474 |
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