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Characterization of oligonucleotide transport into living cells.

Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These compounds are taken up by cells in a saturable, size-dependent manner compatible with receptor-mediate...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, Cohen, J S, Neckers, L M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3474
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