Characterization of oligonucleotide transport into living cells.

Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These compounds are taken up by cells in a saturable, size-dependent manner compatible with receptor-mediate...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, Cohen, J S, Neckers, L M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3474
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