Structure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm Proteins

In eukaryotes, DNA replication is fired once in a single cell cycle before cell division starts to maintain stability of the genome. This event is tightly controlled by a series of proteins. Cdt1 is one of the licensing factors and is involved in recruiting replicative DNA helicase Mcm2–7 proteins i...

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Detalhes bibliográficos
Main Authors: Jee, JunGoo, Mizuno, Takeshi, Kamada, Katsuhiko, Tochio, Hidehito, Chiba, Yasumasa, Yanagi, Ken-ichiro, Yasuda, Gentaro, Hiroaki, Hidekazu, Hanaoka, Fumio, Shirakawa, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871461/
https://ncbi.nlm.nih.gov/pubmed/20335175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.075333
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