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Characterization of conserved arginine residues on Cdt1 that affect licensing activity and interaction with Geminin or Mcm complex

All organisms ensure once and only once replication during S phase through a process called replication licensing. Cdt1 is a key component and crucial loading factor of Mcm complex, which is a central component for the eukaryotic replicative helicase. In higher eukaryotes, timely inhibition of Cdt1...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: You, Zhiying, Ode, Koji L., Shindo, Mayumi, Takisawa, Haruhiko, Masai, Hisao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889252/
https://ncbi.nlm.nih.gov/pubmed/26940553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1106652
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