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Characterization of conserved arginine residues on Cdt1 that affect licensing activity and interaction with Geminin or Mcm complex
All organisms ensure once and only once replication during S phase through a process called replication licensing. Cdt1 is a key component and crucial loading factor of Mcm complex, which is a central component for the eukaryotic replicative helicase. In higher eukaryotes, timely inhibition of Cdt1...
Shranjeno v:
| izdano v: | Cell Cycle |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889252/ https://ncbi.nlm.nih.gov/pubmed/26940553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1106652 |
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