In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway

Many therapeutic proteins are glycosylated and require terminal sialylation to attain full biological activity. Current manufacturing methods based on mammalian cell culture allow only limited control of this important posttranslational modification, which may lead to the generation of products with...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Castilho, Alexandra, Strasser, Richard, Stadlmann, Johannes, Grass, Josephine, Jez, Jakub, Gattinger, Pia, Kunert, Renate, Quendler, Heribert, Pabst, Martin, Leonard, Renaud, Altmann, Friedrich, Steinkellner, Herta
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871460/
https://ncbi.nlm.nih.gov/pubmed/20305285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088401
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi