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Direct determination of molecular haplotypes by chromosome microdissection
Direct observation of haplotypes is still technical challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determine human haplotypes with more than 98.85% accuracy at 24,245 heterozygous single-nucleotide polymorphism (SNP) loci in genome-wid...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871314/ https://ncbi.nlm.nih.gov/pubmed/20305652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1443 |
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