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Direct determination of molecular haplotypes by chromosome microdissection

Direct observation of haplotypes is still technical challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determine human haplotypes with more than 98.85% accuracy at 24,245 heterozygous single-nucleotide polymorphism (SNP) loci in genome-wid...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ma, Li, Xiao, Yan, Huang, Hui, Wang, Qingwei, Rao, Weinian, Feng, Yue, Zhang, Kui, Song, Qing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871314/
https://ncbi.nlm.nih.gov/pubmed/20305652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1443
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