The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1

The transcription factor growth factor independence 1 (Gfi1) and the growth factor granulocyte colony-stimulating factor (G-CSF) are individually essential for neutrophil differentiation from myeloid progenitors. Here, we provide evidence that the functions of Gfi1 and G-CSF are linked in the regula...

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Detaylı Bibliyografya
Asıl Yazarlar: de la Luz Sierra, Maria, Sakakibara, Shuhei, Gasperini, Paola, Salvucci, Ombretta, Jiang, Kan, McCormick, Peter J., Segarra, Marta, Stone, Jim, Maric, Dragan, Zhu, Jinfang, Qian, Xiaolan, Lowy, Douglas R., Tosato, Giovanna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2010
Konular:
Phagocytes, Granulocytes, and Myelopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869559/
https://ncbi.nlm.nih.gov/pubmed/20203268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246967
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