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Perspectives for Computer Modeling in the Study of T Cell Activation

The T cell receptor (TCR) is responsible for discriminating between self- and foreign-derived peptides, translating minute differences in amino-acid sequence into large differences in response. Because of the great variability in the TCR and its ligands, activation of T cells by foreign peptides is...

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Detalhes bibliográficos
Main Authors: Coward, Jesse, Germain, Ronald N., Altan-Bonnet, Grégoire
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869519/
https://ncbi.nlm.nih.gov/pubmed/20516137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a005538
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