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Variability and Robustness in T Cell Activation from Regulated Heterogeneity in Protein Levels
In T cells, the stochasticity of protein expression could contribute to the useful diversification of biological functions within a clonal population or interfere with accurate antigen discrimination. Combining computer modeling and single-cell measurements, we examined how endogenous variation in t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673522/ https://ncbi.nlm.nih.gov/pubmed/18719282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1158013 |
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