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Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression
Concurrent treatment with the methylating agent temozolomide (TMZ) during radiotherapy (RT) has yielded the first significant improvement in survival of adult glioblastomas (GBMs) in the last three decades. However, improved survival is observed in a minority of patients, most frequently those whose...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869471/ https://ncbi.nlm.nih.gov/pubmed/20457618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0010 |
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