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Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approach

Background: The aim of our study was to determine the impact of CYP3A5*1 and CYP3A5*3 on the kinetics of tacrolimus in renal transplant recipients. Material and methods: Forty kidney recipients were selected to participate. Maintenance scheme consisted of tacrolimus, a purine inhibitor and a steroid...

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Detalhes bibliográficos
Main Authors: Katsakiori, Paraskevi F., Papapetrou, Eirini P., Sakellaropoulos, George C., Goumenos, Dimitrios S., Nikiforidis, George C., Flordellis, Christodoulos S.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869454/
https://ncbi.nlm.nih.gov/pubmed/20479955
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