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Discovery of Novel Types of Inhibitors of S-Adenosylmethionine Synthesis by Virtual Screening
S-adenosylmethionine (AdoMet) lies at an intersection of nucleotide and amino acid metabolism, and performs a multitude of metabolic functions. AdoMet formation is catalyzed by S-adenosylmethionine synthetase (ATP : L-methionine S-adenosyltransferase (MAT)) which is a target for development of anti-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869451/ https://ncbi.nlm.nih.gov/pubmed/19739644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9006142 |
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