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Novel Virtual Screening Approach for the Discovery of Human Tyrosinase Inhibitors

Tyrosinase is the key enzyme involved in the human pigmentation process, as well as the undesired browning of fruits and vegetables. Compounds inhibiting tyrosinase catalytic activity are an important class of cosmetic and dermatological agents which show high potential as depigmentation agents used...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ai, Ni, Welsh, William J., Santhanam, Uma, Hu, Hong, Lyga, John
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245091/
https://ncbi.nlm.nih.gov/pubmed/25426625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112788
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