Discovery of novel inhibitors of human galactokinase by virtual screening

Classic Galactosemia is a potentially lethal autosomal recessive metabolic disorder caused by deficient galactose-1-phosphate uridyltransferase (GALT) that results in the buildup of galactose-1-phosphate (gal-1-p) in cells. Galactokinase (GALK1) is the enzyme responsible for converting galactose int...

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Detaylı Bibliyografya
Yayımlandı:J Comput Aided Mol Des
Asıl Yazarlar: Hu, Xin, Zhang, Ya-Qin, Lee, Olivia W., Liu, Li, Tang, Manshu, Lai, Kent, Boxer, Matthew B., Hall, Matthew D., Shen, Min
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459016/
https://ncbi.nlm.nih.gov/pubmed/30806949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00190-3
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