Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy.

The effects of intravenous administration of prostaglandins (PGs) were investigated in genetically narcoleptic Doberman pinschers. The treatment of narcoleptic dogs with PGE2 and PGE2 methyl ester, but not PGD2 and PGD2 methyl ester, induced a dose-dependent reduction of canine cataplexy, a dissocia...

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Bibliografiske detaljer
Main Authors: Nishino, S, Mignot, E, Fruhstorfer, B, Dement, W C, Hayaishi, O
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC286937/
https://ncbi.nlm.nih.gov/pubmed/2928344
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