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Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy.

The effects of intravenous administration of prostaglandins (PGs) were investigated in genetically narcoleptic Doberman pinschers. The treatment of narcoleptic dogs with PGE2 and PGE2 methyl ester, but not PGD2 and PGD2 methyl ester, induced a dose-dependent reduction of canine cataplexy, a dissocia...

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Bibliografske podrobnosti
Main Authors: Nishino, S, Mignot, E, Fruhstorfer, B, Dement, W C, Hayaishi, O
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC286937/
https://ncbi.nlm.nih.gov/pubmed/2928344
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