Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens

[Image: see text] Described is an efficient heterologous expression system for Sulfolobus solfataricus ADH-10 (Alcohol Dehydrogenase isozyme 10) and its use in the dynamic reductive kinetic resolution (DYRKR) of 2-arylpropanal (Profen-type) substrates. Importantly, among the 12 aldehydes tested, a g...

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Detaylı Bibliyografya
Asıl Yazarlar: Friest, Jacob A., Maezato, Yukari, Broussy, Sylvain, Blum, Paul, Berkowitz, David B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2010
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869291/
https://ncbi.nlm.nih.gov/pubmed/20377222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910778p
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