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Halocarbocyclization Entry into the Oxabicyclo[4.3.1]decyl Exomethylene-δ-Lactone Cores of Linearifolin and Zaluzanin A - Exploiting Combinatorial Catalysis

[Image: see text] A streamlined entry into the sesquiterpene lactones (SQL) cores of linearifolin and zaluzanin A is described. Stereochemistry is controlled through transformations uncovered by ISES (In-Situ-Enzymatic-Screening). Absolute stereochemistry derives from kinetic resolution of 5-benzylo...

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Detalhes bibliográficos
Main Authors: Ginotra, Sandeep K., Friest, Jacob A., Berkowitz, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289138/
https://ncbi.nlm.nih.gov/pubmed/22316136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol203088g
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