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Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens
[Image: see text] Described is an efficient heterologous expression system for Sulfolobus solfataricus ADH-10 (Alcohol Dehydrogenase isozyme 10) and its use in the dynamic reductive kinetic resolution (DYRKR) of 2-arylpropanal (Profen-type) substrates. Importantly, among the 12 aldehydes tested, a g...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Chemical Society
2010
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869291/ https://ncbi.nlm.nih.gov/pubmed/20377222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910778p |
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