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Towards the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks

The monosaccharide moieties found in heparin (HP) and heparan sulfate (HS), glucosamine and two kinds of uronic acids, glucuronic and iduronic acids, were efficiently synthesized by use of glucosamine hydrochloride and glucurono-6,3-lactone as starting compounds. In the synthesis of the disaccharide...

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Bibliografiske detaljer
Main Authors: Saito, Akihiro, Wakao, Masahiro, Deguchi, Hiroshi, Mawatari, Aya, Sobel, Michael, Suda, Yasuo
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869207/
https://ncbi.nlm.nih.gov/pubmed/20473366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.03.077
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