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Brg1 Is Required for Cdx2-Mediated Repression of Oct4 Expression in Mouse Blastocysts

During blastocyst formation the segregation of the inner cell mass (ICM) and trophectoderm is governed by the mutually antagonistic effects of the transcription factors Oct4 and Cdx2. Evidence indicates that suppression of Oct4 expression in the trophectoderm is mediated by Cdx2. Nonetheless, the un...

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Bibliographic Details
Main Authors: Wang, Kai, Sengupta, Satyaki, Magnani, Luca, Wilson, Catherine A., Henry, R. William, Knott, Jason G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868905/
https://ncbi.nlm.nih.gov/pubmed/20485553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010622
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