High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

Chromatin acts as a key regulator of DNA-related processes such as DNA damage repair. Although ChIP-chip is a powerful technique to provide high-resolution maps of protein–genome interactions, its use to study DNA double strand break (DSB) repair has been hindered by the limitations of the available...

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Main Authors: Iacovoni, Jason S, Caron, Pierre, Lassadi, Imen, Nicolas, Estelle, Massip, Laurent, Trouche, Didier, Legube, Gaëlle
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868577/
https://ncbi.nlm.nih.gov/pubmed/20360682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.38
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