p16(INK4a )hypermethylation and p53, p16 and MDM2 protein expression in Esophageal Squamous Cell Carcinoma

BACKGROUND: Tumor suppressor genes p53 and p16(INK4a )and the proto-oncogene MDM2 are considered to be essential G1 cell cycle regulatory genes whose loss of function is associated with ESCC carcinogenesis. We assessed the aberrant methylation of the p16 gene and its impact on p16(INK4a )protein exp...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Taghavi, Noushin, Biramijamal, Firouzeh, Sotoudeh, Masoud, Khademi, Hooman, Malekzadeh, Reza, Moaven, Omeed, Memar, Bahram, A'rabi, Azadeh, Abbaszadegan, Mohammad Reza
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868052/
https://ncbi.nlm.nih.gov/pubmed/20388212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-138
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы