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Rapamycin Inhibits IGF-1 Stimulated Cell Motility through PP2A Pathway
Serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A) has been implicated as a novel component of the mammalian target of rapamycin (mTOR) signaling pathway. Recently we have demonstrated that mTOR regulates cell motility in part through p70 S6 kinase 1 (S6K1) and eukaryotic initiation factor 4E...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868031/ https://ncbi.nlm.nih.gov/pubmed/20485667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010578 |
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