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Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells

Dihydroartemisinin (DHA), an antimalarial drug, has previously unrecognized anticancer activity, and is in clinical trials as a new anticancer agent for skin, lung, colon and breast cancer treatment. However, the anticancer mechanism is not well understood. Here, we show that DHA inhibited prolifera...

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Autori principali: Odaka, Yoshinobu, Xu, Baoshan, Luo, Yan, Shen, Tao, Shang, Chaowei, Wu, Yang, Zhou, Hongyu, Huang, Shile
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871936/
https://ncbi.nlm.nih.gov/pubmed/23929438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt277
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