Rapamycin Inhibits IGF-1 Stimulated Cell Motility through PP2A Pathway

Serine/threonine (Ser/Thr) protein phosphatase 2A (PP2A) has been implicated as a novel component of the mammalian target of rapamycin (mTOR) signaling pathway. Recently we have demonstrated that mTOR regulates cell motility in part through p70 S6 kinase 1 (S6K1) and eukaryotic initiation factor 4E...

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Autors principals: Liu, Lei, Chen, Long, Luo, Yan, Chen, Wenxing, Zhou, Hongyu, Xu, Baoshan, Han, Xiuzhen, Shen, Tao, Huang, Shile
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868031/
https://ncbi.nlm.nih.gov/pubmed/20485667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010578
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