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A feed-forward loop amplifies nutritional regulation of PNPLA3
The upsurge in prevalence of obesity has spawned an epidemic of nonalcoholic fatty liver disease (NAFLD). Previously, we identified a sequence variant (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) that confers susceptibility to both hepatic triglyceride (TG) deposition a...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867902/ https://ncbi.nlm.nih.gov/pubmed/20385813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003585107 |
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