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Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression

Early B cell factor (EBF)1 is essential for B lineage specification. Previously, we demonstrated the synergistic activation of Cd79a (mb-1) genes by EBF1 and its functional partner, RUNX1. Here, we identified consequences of Ebf1 haploinsufficiency together with haploinsufficiency of Runx1 genes in...

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Detaylı Bibliyografya
Asıl Yazarlar: Lukin, Kara, Fields, Scott, Lopez, Desiree, Cherrier, Marie, Ternyak, Kristina, Ramírez, Julita, Feeney, Ann J., Hagman, James
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867885/
https://ncbi.nlm.nih.gov/pubmed/20385820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003525107
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