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Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression
Early B cell factor (EBF)1 is essential for B lineage specification. Previously, we demonstrated the synergistic activation of Cd79a (mb-1) genes by EBF1 and its functional partner, RUNX1. Here, we identified consequences of Ebf1 haploinsufficiency together with haploinsufficiency of Runx1 genes in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867885/ https://ncbi.nlm.nih.gov/pubmed/20385820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003525107 |
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