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A dose-dependent role for EBF1 in repressing non-B cell specific genes

In the absence of EBF1, B cell development is arrested at an uncommitted progenitor stage that exhibits increased lineage potentials. Previously, we investigated the roles of EBF1 (E) and its DNA binding partner Runx1 (R) by evaluating B lymphopoiesis in single (E(het) and R(het)) and compound haplo...

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Hlavní autoři: Lukin, Kara, Fields, Scott, Guerrettaz, Lisa, Straign, Desiree, Rodriguez, Valerie, Zandi, Sasan, Månsson, Robert, Cambier, John C., Sigvardsson, Mikael, Hagman, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127254/
https://ncbi.nlm.nih.gov/pubmed/21469119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041137
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