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From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment
The generation of B lymphocytes from hematopoietic progenitors requires lineage-specific transcription factors that progressively direct cell fate choices. Differentiation of hematopoietic stem cells to lymphoid progenitors requires Ikaros-dependent lineage priming and graded levels of PU.1, which a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854230/ https://ncbi.nlm.nih.gov/pubmed/20207529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.02.003 |
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