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Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.

A hybrid enzyme consisting of an oligodeoxyribonucleotide fused to a unique site on staphylococcal nuclease site-selectively cleaves a number of natural RNAs including Escherichia coli M1 RNA (377 bases), 16S rRNA (1542 bases), and yeast tRNA(Phe). The oligonucleotide directs the nuclease activity o...

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Bibliografiska uppgifter
Huvudupphovsmän: Zuckermann, R N, Schultz, P G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC286785/
https://ncbi.nlm.nih.gov/pubmed/2467291
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