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Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.

A hybrid enzyme consisting of an oligodeoxyribonucleotide fused to a unique site on staphylococcal nuclease site-selectively cleaves a number of natural RNAs including Escherichia coli M1 RNA (377 bases), 16S rRNA (1542 bases), and yeast tRNA(Phe). The oligonucleotide directs the nuclease activity o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Zuckermann, R N, Schultz, P G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2467291/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1766
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