Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.
A hybrid enzyme consisting of an oligodeoxyribonucleotide fused to a unique site on staphylococcal nuclease site-selectively cleaves a number of natural RNAs including Escherichia coli M1 RNA (377 bases), 16S rRNA (1542 bases), and yeast tRNA(Phe). The oligonucleotide directs the nuclease activity o...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2467291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1766 |
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