Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.

A hybrid enzyme consisting of an oligodeoxyribonucleotide fused to a unique site on staphylococcal nuclease site-selectively cleaves a number of natural RNAs including Escherichia coli M1 RNA (377 bases), 16S rRNA (1542 bases), and yeast tRNA(Phe). The oligonucleotide directs the nuclease activity o...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Zuckermann, R N, Schultz, P G
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1989
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2467291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1766
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