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Replication independent DNA double-strand break retention may prevent genomic instability
BACKGROUND: Global hypomethylation and genomic instability are cardinal features of cancers. Recently, we established a method for the detection of DNA methylation levels at sites close to endogenous DNA double strand breaks (EDSBs), and found that those sites have a higher level of methylation than...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867818/ https://ncbi.nlm.nih.gov/pubmed/20356374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-70 |
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