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Characteristics of replication-independent endogenous double-strand breaks in Saccharomyces cerevisiae

BACKGROUND: Replication-independent endogenous double-strand breaks (RIND-EDSBs) occur in both humans and yeast in the absence of inductive agents and DNA replication. In human cells, RIND-EDSBs are hypermethylated, preferentially retained in the heterochromatin and unbound by γ-H2AX. In single gene...

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Autori principali: Pongpanich, Monnat, Patchsung, Maturada, Thongsroy, Jirapan, Mutirangura, Apiwat
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158086/
https://ncbi.nlm.nih.gov/pubmed/25179264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-750
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