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Characteristics of replication-independent endogenous double-strand breaks in Saccharomyces cerevisiae
BACKGROUND: Replication-independent endogenous double-strand breaks (RIND-EDSBs) occur in both humans and yeast in the absence of inductive agents and DNA replication. In human cells, RIND-EDSBs are hypermethylated, preferentially retained in the heterochromatin and unbound by γ-H2AX. In single gene...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158086/ https://ncbi.nlm.nih.gov/pubmed/25179264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-750 |
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