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Replication-Independent Endogenous DNA Double-Strand Breaks in Saccharomyces cerevisiae Model
Without exposure to any DNA-damaging agents, non-dividing eukaryotic cells carry endogenous DNA double-strand breaks (EDSBs), or Replication-Independent (RIND)-EDSBs. In human cells, RIND-EDSBs are enriched in the methylated heterochromatic areas of the genome and are repaired by an ATM-dependent no...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747138/ https://ncbi.nlm.nih.gov/pubmed/23977341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072706 |
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