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Replication-Independent Endogenous DNA Double-Strand Breaks in Saccharomyces cerevisiae Model

Without exposure to any DNA-damaging agents, non-dividing eukaryotic cells carry endogenous DNA double-strand breaks (EDSBs), or Replication-Independent (RIND)-EDSBs. In human cells, RIND-EDSBs are enriched in the methylated heterochromatic areas of the genome and are repaired by an ATM-dependent no...

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Hlavní autoři: Thongsroy, Jirapan, Matangkasombut, Oranart, Thongnak, Araya, Rattanatanyong, Prakasit, Jirawatnotai, Siwanon, Mutirangura, Apiwat
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747138/
https://ncbi.nlm.nih.gov/pubmed/23977341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072706
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