Evolutionary dynamics of Clostridium difficile over short and long time scales

Clostridium difficile has rapidly emerged as the leading cause of antibiotic-associated diarrheal disease, with the transcontinental spread of various PCR ribotypes, including 001, 017, 027 and 078. However, the genetic basis for the emergence of C. difficile as a human pathogen is unclear. Whole ge...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: He, Miao, Sebaihia, Mohammed, Lawley, Trevor D., Stabler, Richard A., Dawson, Lisa F., Martin, Melissa J., Holt, Kathryn E., Seth-Smith, Helena M.B., Quail, Michael A., Rance, Richard, Brooks, Karen, Churcher, Carol, Harris, David, Bentley, Stephen D., Burrows, Christine, Clark, Louise, Corton, Craig, Murray, Vicky, Rose, Graham, Thurston, Scott, van Tonder, Andries, Walker, Danielle, Wren, Brendan W., Dougan, Gordon, Parkhill, Julian
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2010
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867753/
https://ncbi.nlm.nih.gov/pubmed/20368420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914322107
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