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In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions

Previously, we demonstrated that the recently evolved PCR-ribotype 027 hypervirulent Clostridium difficile strain (R20291) has acquired five genetic regions compared to the historic 027 counterpart strain (CD196), that may in part explain phenotypic traits relating to survival, antimicrobial resista...

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Библиографические подробности
Главные авторы: Stabler, Richard A, Valiente, Esmeralda, Dawson, Lisa F, He, Miao, Parkhill, Julian, Wren, Brendan W
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023608/
https://ncbi.nlm.nih.gov/pubmed/21327033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.1.4.11870
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