Evolutionary dynamics of Clostridium difficile over short and long time scales

Clostridium difficile has rapidly emerged as the leading cause of antibiotic-associated diarrheal disease, with the transcontinental spread of various PCR ribotypes, including 001, 017, 027 and 078. However, the genetic basis for the emergence of C. difficile as a human pathogen is unclear. Whole ge...

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Detalhes bibliográficos
Main Authors: He, Miao, Sebaihia, Mohammed, Lawley, Trevor D., Stabler, Richard A., Dawson, Lisa F., Martin, Melissa J., Holt, Kathryn E., Seth-Smith, Helena M.B., Quail, Michael A., Rance, Richard, Brooks, Karen, Churcher, Carol, Harris, David, Bentley, Stephen D., Burrows, Christine, Clark, Louise, Corton, Craig, Murray, Vicky, Rose, Graham, Thurston, Scott, van Tonder, Andries, Walker, Danielle, Wren, Brendan W., Dougan, Gordon, Parkhill, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867753/
https://ncbi.nlm.nih.gov/pubmed/20368420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914322107
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