Evolutionary dynamics of Clostridium difficile over short and long time scales

Clostridium difficile has rapidly emerged as the leading cause of antibiotic-associated diarrheal disease, with the transcontinental spread of various PCR ribotypes, including 001, 017, 027 and 078. However, the genetic basis for the emergence of C. difficile as a human pathogen is unclear. Whole ge...

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Autors principals: He, Miao, Sebaihia, Mohammed, Lawley, Trevor D., Stabler, Richard A., Dawson, Lisa F., Martin, Melissa J., Holt, Kathryn E., Seth-Smith, Helena M.B., Quail, Michael A., Rance, Richard, Brooks, Karen, Churcher, Carol, Harris, David, Bentley, Stephen D., Burrows, Christine, Clark, Louise, Corton, Craig, Murray, Vicky, Rose, Graham, Thurston, Scott, van Tonder, Andries, Walker, Danielle, Wren, Brendan W., Dougan, Gordon, Parkhill, Julian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867753/
https://ncbi.nlm.nih.gov/pubmed/20368420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914322107
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