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Lethal mutagenesis in a structured environment
We analyze how lethal mutagenesis operates in a compartmentalized host. We assume that different compartments receive different amounts of mutagen and that virions can migrate among compartments. We address two main questions: 1. To what extent can refugia, i.e., compartments that receive little mut...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
2009
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867491/ https://ncbi.nlm.nih.gov/pubmed/19627995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.07.014 |
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