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Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-(13)C]pyruvate

Carbon 13 nuclear magnetic resonance (NMR) isotopomer analysis was used to measure the rates of oxidation of long-chain fatty acids, ketones, and pyruvate to determine the minimum pyruvate concentration ([pyruvate]) needed to suppress oxidation of these alternative substrates. Substrate mixtures wer...

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Autores principales: Moreno, Karlos X., Sabelhaus, Scott M., Merritt, Matthew E., Sherry, A. Dean, Malloy, Craig R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867437/
https://ncbi.nlm.nih.gov/pubmed/20207817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00656.2009
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